8D3E: Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with 6-fluoroquinolin-4-amine

PDB ID: 8D3EDownload
MMDB ID: 238179
PDB Deposition Date: 2022/6/1
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.38  Å
Source Organism:
Similar Structures:
Biological Unit for 8D3E: dimeric; determined by author
Molecular Components in 8D3E
Label Count Molecule
Proteins (2 molecules)
2
Apoptosis-inducing Factor 1, Mitochondrial
(Gene symbol: AIFM1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
1
6-fluoroquinolin-4-amine6-fluoroquinolin-4-amine
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303