8CZZ: Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074

PDB ID: 8CZZDownload
MMDB ID: 230827
PDB Deposition Date: 2022/5/25
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3.14  Å
Source Organism:
Human immunodeficiency virus 1▼
Similar Structures:
Biological Unit for 8CZZ: octadecameric; determined by author
Molecular Components in 8CZZ
Label Count Molecule
Proteins (18 molecules)
3
Crf01_ae T/f100 Hiv-1 Gp120
Molecule annotation
3
Crf-1_ae T/f100 Hiv-1 Gp41
Molecule annotation
3
Heavy Chain of 8anc195 FAB
Molecule annotation
3
Light Chain of 8anc195 FAB
Molecule annotation
3
Heavy Chain of 10-1074 FAB
Molecule annotation
3
Light Chain of 10-1074 FAB
Molecule annotation
Chemicals and Non-standard biopolymers (138 molecules)
1
94
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
12
beta-D-mannopyranosebeta-D-mannopyranose
3
29
alpha-D-mannopyranosealpha-D-mannopyranose
4
3
1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303