8CYH: Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics

PDB ID: 8CYHDownload
MMDB ID: 231126
PDB Deposition Date: 2022/5/23
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.38  Å
Source Organism:
Similar Structures:
Biological Unit for 8CYH: trimeric; determined by author
Molecular Components in 8CYH
Label Count Molecule
Proteins (3 molecules)
1
A12 Antibody Light Chain
Molecule annotation
1
A12 Antibody Heavy Chain
Molecule annotation
1
Mesothelin, Cleaved Form
(Gene symbol: MSLN)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303