8CXC: Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics

PDB ID: 8CXCDownload
MMDB ID: 231122
PDB Deposition Date: 2022/5/20
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 4.31  Å
Source Organism:
Mus musculus▼
Similar Structures:
Molecular Components in 8CXC
Label Count Molecule
Proteins (4 molecules)
1
3F2 Antibody Light Chain
Molecule annotation
1
3F2 Antibody Heavy Chain
Molecule annotation
1
Mesothelin, Cleaved Form
Molecule annotation
1
Scfv Amatuximab
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303