8CW2: Crystal structure of TDP1 complexed with compound XZ760

PDB ID: 8CW2Download
MMDB ID: 228960
PDB Deposition Date: 2022/5/18
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.811  Å
Source Organism:
Similar Structures:
Biological Unit for 8CW2: monomeric; determined by author and by software (PISA)
Molecular Components in 8CW2
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 1
(Gene symbol: TDP1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
4-({(4R)-7-phenyl-2-[4-(2-{[4-(pyridin-2-yl)phenyl]methoxy}ethyl)phenyl]imidazo[1,2-a]pyridin-3-yl}amino)benzene-1,2-dicarboxylic acid4-({(4R)-7-phenyl-2-[4-(2-{[4-(pyridin-2-yl)phenyl]methoxy}ethyl)phenyl]imidazo[1,2-a]pyridin-3-yl}amino)benzene-1,2-dicarboxylic acid
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
3[N-MORPHOLINO]PROPANE SULFONIC ACID3[N-MORPHOLINO]PROPANE SULFONIC ACID
4
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303