8CRH: Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and cycloguanil

PDB ID: 8CRHDownload
MMDB ID: 233553
PDB Deposition Date: 2023/3/8
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8CRH: dimeric; determined by author
Molecular Components in 8CRH
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
4
5-(4-chlorophenyl)-6,6-dimethyl-1,4-dihydro-1,3,5-triazine-2,4-diamine5-(4-chlorophenyl)-6,6-dimethyl-1,4-dihydro-1,3,5-triazine-2,4-diamine
2
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303