8CR0: Crystal structure of human carbonic anhydrase II in complex with a triazolyl benzoxaborole inhibitor

PDB ID: 8CR0Download
MMDB ID: 231866
PDB Deposition Date: 2023/3/7
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.22  Å
Source Organism:
Similar Structures:
Biological Unit for 8CR0: monomeric; determined by author and by software (PISA)
Molecular Components in 8CR0
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
1-[1,1-bis(oxidanyl)-3~{H}-2,1$l^{4}-benzoxaborol-6-yl]-4-[(4-fluoranylphenoxy)methyl]-1,2,3-triazole1-[1,1-bis(oxidanyl)-3~{H}-2,1$l^{4}-benzoxaborol-6-yl]-4-[(4-fluoranylphenoxy)methyl]-1,2,3-triazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303