8CQI: Human heparanase in complex with inhibitor R3794

PDB ID: 8CQIDownload
MMDB ID: 240975
PDB Deposition Date: 2023/3/6
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8CQI: dimeric; determined by author
Molecular Components in 8CQI
Label Count Molecule
Proteins (2 molecules)
1
Heparanase 50 KDA Subunit
(Gene symbol: HPSE)
Molecule annotation
1
Heparanase
(Gene symbol: HPSE)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
(3~{S},4~{S})-4,5,5-tris(oxidanyl)piperidine-3-carboxylic acid(3~{S},4~{S})-4,5,5-tris(oxidanyl)piperidine-3-carboxylic acid
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
1,5-anhydro-D-arabinitol1,5-anhydro-D-arabinitol
5
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303