8COT: Complex of human soluble adenylyl cyclase 10 catalytic core with inhibitor TDI-10962

PDB ID: 8COTDownload
MMDB ID: 229556
PDB Deposition Date: 2023/2/28
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8COT: monomeric; determined by author
Molecular Components in 8COT
Label Count Molecule
Protein (1 molecule)
1
Adenylate Cyclase Type 10
(Gene symbol: ADCY10)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
2-(dimethylamino)ethyl 5-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-2-methyl-4-(phenylmethyl)pyrazole-3-carboxylate2-(dimethylamino)ethyl 5-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-2-methyl-4-(phenylmethyl)pyrazole-3-carboxylate
2
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
5
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303