8COJ: Crystal structure of human soluble adenylyl cyclase catalytic domain in complex with the inhibitor TDI-10228

PDB ID: 8COJDownload
MMDB ID: 229555
PDB Deposition Date: 2023/2/28
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8COJ: monomeric; determined by author and by software (PISA)
Molecular Components in 8COJ
Label Count Molecule
Protein (1 molecule)
1
Adenylate Cyclase Type 10
(Gene symbol: ADCY10)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
4-chloranyl-6-[4-[(3-fluorophenyl)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-amine4-chloranyl-6-[4-[(3-fluorophenyl)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-amine
2
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
ACETATE IONACETATE ION
4
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303