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8COJ:
Crystal structure of human soluble adenylyl cyclase catalytic domain in complex with the inhibitor TDI-10228
PDB ID:
8COJ
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MMDB ID:
229555
PDB Deposition Date:
2023/2/28
Updated in MMDB:
2024/10
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 8COJ: monomeric; determined by author and by software (PISA)
Molecular Components in 8COJ
Label
Count
Molecule
Protein (1 molecule)
A
1
Adenylate Cyclase Type 10
(Gene symbol:
ADCY10
)
Chemicals and Non-standard biopolymers (12 molecules)
1
1
4-chloranyl-6-[4-[(3-fluorophenyl)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-amine
2
4
DIMETHYL SULFOXIDE
3
1
ACETATE ION
4
6
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303