8CO0: Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide

PDB ID: 8CO0Download
MMDB ID: 239661
PDB Deposition Date: 2023/2/25
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8CO0: tetrameric; determined by author
Molecular Components in 8CO0
Label Count Molecule
Proteins (4 molecules)
4
Carbonic Anhydrase 9
(Gene symbol: CA9)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
ZINC IONZINC ION
2
4
5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide
3
4
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303