8CNH: Crystal structure of human soluble adenylyl cyclase (sAC) in complex with inhibitor TDI-10512

PDB ID: 8CNHDownload
MMDB ID: 229554
PDB Deposition Date: 2023/2/23
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8CNH: monomeric; determined by author
Molecular Components in 8CNH
Label Count Molecule
Protein (1 molecule)
1
Adenylate Cyclase Type 10
(Gene symbol: ADCY10)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
methyl 2-[[3-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-1-methyl-pyrazol-4-yl]methyl]benzoatemethyl 2-[[3-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-1-methyl-pyrazol-4-yl]methyl]benzoate
2
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303