8CK4: STRUCTURE OF HIF2A-ARNT HETERODIMER IN COMPLEX WITH (4S)-1-(3,5-difluorophenyl)-5,5-difluoro-3-methanesulfonyl-4,5,6,7-tetrahydro-2-benzothiophen-4-ol

PDB ID: 8CK4Download
MMDB ID: 233011
PDB Deposition Date: 2023/2/14
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8CK4: dimeric; determined by author and by software (PISA)
Molecular Components in 8CK4
Label Count Molecule
Proteins (2 molecules)
1
Endothelial PAS Domain-containing Protein 1
(Gene symbol: EPAS1)
Molecule annotation
1
Aryl Hydrocarbon Receptor Nuclear Translocator
(Gene symbol: ARNT)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4~{S})-1-[3,5-bis(fluoranyl)phenyl]-5,5-bis(fluoranyl)-3-methylsulfonyl-6,7-dihydro-4~{H}-2-benzothiophen-4-ol(4~{S})-1-[3,5-bis(fluoranyl)phenyl]-5,5-bis(fluoranyl)-3-methylsulfonyl-6,7-dihydro-4~{H}-2-benzothiophen-4-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303