8CJ7: HDAC6 selective degraded (difluoromethyl)-1,3,4-oxadiazole substrate inhibitor

PDB ID: 8CJ7Download
MMDB ID: 236760
PDB Deposition Date: 2023/2/12
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.51  Å
Source Organism:
Similar Structures:
Biological Unit for 8CJ7: monomeric; determined by author
Molecular Components in 8CJ7
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 6
(Gene symbol: hdac6)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
POTASSIUM IONPOTASSIUM ION
2
1
ZINC IONZINC ION
3
1
6-[(5-pyridin-2-yl-1,2$l^{4},3,4-tetrazacyclopenta-1,3-dien-2-yl)methyl]pyridine-3-carbohydrazide6-[(5-pyridin-2-yl-1,2$l^{4},3,4-tetrazacyclopenta-1,3-dien-2-yl)methyl]pyridine-3-carbohydrazide
4
3
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303