8CI1: Human alpha7 nicotinic receptor in complex with the E3 nanobody and nicotine

PDB ID: 8CI1Download
MMDB ID: 236543
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8CI1: decameric; determined by author and by software (PISA)
Molecular Components in 8CI1
Label Count Molecule
Proteins (10 molecules)
5
Neuronal Acetylcholine Receptor Subunit Alpha-7
(Gene symbol: CHRNA7)
Molecule annotation
5
Nanobody E3
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303