8CHF: cryo-EM Structure of Craf:14-3-3:Mek1

PDB ID: 8CHFDownload
MMDB ID: 242935
PDB Deposition Date: 2023/2/7
Updated in MMDB: 2024/03
Experimental Method:
electron microscopy
Resolution: 4.25  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 8CHF: hexameric; determined by author and by software (PISA)
Molecular Components in 8CHF
Label Count Molecule
Proteins (6 molecules)
2
RAF Proto-oncogene Serine/threonine-protein Kinase
Molecule annotation
2
14-3-3 Protein Zeta Isoform X1
Molecule annotation
2
Dual Specificity Mitogen-activated Protein Kinase Kinase 1
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303