8CH8: Crystal structure of the human PXR ligand-binding domain in complex with liranaftate

PDB ID: 8CH8Download
MMDB ID: 242932
PDB Deposition Date: 2023/2/7
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 8CH8: monomeric; determined by author
Molecular Components in 8CH8
Label Count Molecule
Protein (1 molecule)
1
Nuclear Receptor Subfamily 1 Group I Member 2
(Gene symbol: NR1I2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{O}-(5,6,7,8-tetrahydronaphthalen-2-yl) ~{N}-(6-methoxypyridin-2-yl)-~{N}-methyl-carbamothioate~{O}-(5,6,7,8-tetrahydronaphthalen-2-yl) ~{N}-(6-methoxypyridin-2-yl)-~{N}-methyl-carbamothioate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303