8CGC: Structure of CSF1R in complex with a pyrollopyrimidine (compound 23)

PDB ID: 8CGCDownload
MMDB ID: 230498
PDB Deposition Date: 2023/2/3
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 1.925  Å
Source Organism:
Similar Structures:
Biological Unit for 8CGC: monomeric; determined by author
Molecular Components in 8CGC
Label Count Molecule
Protein (1 molecule)
1
Macrophage Colony-stimulating Factor 1 Receptor
(Gene symbol: CSF1R)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2S)-2-hydroxybutanedioic acid(2S)-2-hydroxybutanedioic acid
2
1
GLYCEROLGLYCEROL
3
1
[4-[4-[methyl-[(3-methylphenyl)methyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]methanol[4-[4-[methyl-[(3-methylphenyl)methyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]methanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303