8CER: Crystal structure of monkeypox virus methyltransferase VP39 in complex with inhibitor TO494

PDB ID: 8CERDownload
MMDB ID: 228691
PDB Deposition Date: 2023/2/2
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8CER: monomeric; determined by author
Molecular Components in 8CER
Label Count Molecule
Protein (1 molecule)
1
Cap-specific mRNA (Nucleoside-2'-o-)-methyltransferase
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[4-azanyl-5-(2-naphthalen-1-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid(2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[4-azanyl-5-(2-naphthalen-1-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303