8CDW: CRYSTAL STRUCTURE OF HUMAN HPK1 (MAP4K1) COMPLEX WITH 7-(1-methyl-1H-pyrazol-4-yl)-N-[4-(1-methylpiperidin-4-yl)phenyl]quinazolin-2-amine

PDB ID: 8CDWDownload
MMDB ID: 234193
PDB Deposition Date: 2023/2/1
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.941  Å
Source Organism:
Similar Structures:
Biological Unit for 8CDW: dimeric; determined by author and by software (PISA)
Molecular Components in 8CDW
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1
(Gene symbol: MAP4K1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine~{N}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303