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8C8T:
cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117
PDB ID:
8C8T
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MMDB ID:
232364
PDB Deposition Date:
2023/1/21
Updated in MMDB:
2023/08
Experimental Method:
electron microscopy
Resolution:
3.2 Å
Source Organism:
Human immunodeficiency virus 1
▼
Taxonomy
Molecule
Human immunodeficiency virus 1
A, B, F, G, I, J
Homo sapiens
C, H, R, S, T, U, D, K
Similar Structures:
VAST+
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Biological Unit for 8C8T: 14-meric; determined by author
Molecular Components in 8C8T
Label
Count
Molecule
Proteins (14 molecules)
A
F
G
3
Envelope Glycoprotein Gp160
B
I
J
3
Gp41 Bg505 T332n Sosip.664
C
H
2
IGG Eptc112 FAB Fragment Heavy Chain
R
S
2
IGG 3bnc117 FAB Heavy Chain
T
U
2
IGG 3bnc117 FAB Light Chain
D
K
2
IGG Eptc112 FAB Light Chain
Chemicals and Non-standard biopolymers (56 molecules)
1
52
2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
beta-D-mannopyranose
3
1
alpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303