8C8J: Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP

PDB ID: 8C8JDownload
MMDB ID: 240107
PDB Deposition Date: 2023/1/20
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8C8J: trimeric; determined by author and by software (PISA)
Molecular Components in 8C8J
Label Count Molecule
Protein (1 molecule)
1
RNA-directed DNA Polymerase
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*gp*cp*gp*cp*tp*tp*tp*cp*c)-3')
Molecule annotation
1
RNA (5'-r(p*up*up*ap*gp*gp*ap*ap*ap*gp*cp*gp*c)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (23 molecules)
1
2
CITRIC ACIDCITRIC ACID
2
1
THYMIDINE-5'-TRIPHOSPHATETHYMIDINE-5'-TRIPHOSPHATE
3
14
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
1,4-DIETHYLENE DIOXIDE1,4-DIETHYLENE DIOXIDE
6
2
MAGNESIUM IONMAGNESIUM ION
7
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303