8C8C: Crystal Structure of Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PI5P4Ka) bound to an inhibitor

PDB ID: 8C8CDownload
MMDB ID: 229530
PDB Deposition Date: 2023/1/19
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.096  Å
Source Organism:
Similar Structures:
Biological Unit for 8C8C: dimeric; determined by software (PISA)
Molecular Components in 8C8C
Label Count Molecule
Proteins (2 molecules)
2
Phosphatidylinositol 5-phosphate 4-kinase Type-2 Alpha
(Gene symbol: PIP4K2A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-(3-chloranyl-4-methoxy-phenyl)-7-(3,4-dimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine~{N}-(3-chloranyl-4-methoxy-phenyl)-7-(3,4-dimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303