8C8B: Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 48)

PDB ID: 8C8BDownload
MMDB ID: 241908
PDB Deposition Date: 2023/1/19
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.46  Å
Source Organism:
Similar Structures:
Biological Unit for 8C8B: monomeric; determined by author
Molecular Components in 8C8B
Label Count Molecule
Protein (1 molecule)
1
DNA Cross-link Repair 1A Protein
(Gene symbol: DCLRE1A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-[[(2~{S})-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-~{N}-prop-2-enyl-quinazoline-2-carboxamide4-[[(2~{S})-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-~{N}-prop-2-enyl-quinazoline-2-carboxamide
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303