8C78: Crystal structure of human BCL6 BTB domain in complex with compound CCT374705

PDB ID: 8C78Download
MMDB ID: 229529
PDB Deposition Date: 2023/1/13
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8C78: dimeric; determined by author and by software (PISA)
Molecular Components in 8C78
Label Count Molecule
Proteins (2 molecules)
2
B-cell Lymphoma 6 Protein
(Gene symbol: BCL6)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
(2~{S})-10-[(3-chloranyl-2-fluoranyl-pyridin-4-yl)amino]-2-cyclopropyl-3,3-bis(fluoranyl)-7-methyl-2,4-dihydro-1~{H}-[1,4]oxazepino[2,3-c]quinolin-6-one(2~{S})-10-[(3-chloranyl-2-fluoranyl-pyridin-4-yl)amino]-2-cyclopropyl-3,3-bis(fluoranyl)-7-methyl-2,4-dihydro-1~{H}-[1,4]oxazepino[2,3-c]quinolin-6-one
2
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303