8C4F: Small molecule amidine soak in 14-3-3/ERa (AZ037)

PDB ID: 8C4FDownload
MMDB ID: 233541
PDB Deposition Date: 2023/1/3
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8C4F: tetrameric; determined by author and by software (PISA)
Molecular Components in 8C4F
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Eralpha Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
5-(cyclohexylamino)-4-phenyl-thiophene-2-carboximidamide5-(cyclohexylamino)-4-phenyl-thiophene-2-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303