8C3U: Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist

PDB ID: 8C3UDownload
MMDB ID: 235403
PDB Deposition Date: 2022/12/28
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.945  Å
Source Organism:
Similar Structures:
Biological Unit for 8C3U: monomeric; determined by author
Molecular Components in 8C3U
Label Count Molecule
Protein (1 molecule)
1
Interleukin-1 Beta
(Gene symbol: IL1B)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid(S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303