8C2Z: Crystal structure of DYRK1B in complex with AZ191

PDB ID: 8C2ZDownload
MMDB ID: 241226
PDB Deposition Date: 2022/12/23
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.91  Å
Source Organism:
Similar Structures:
Biological Unit for 8C2Z: monomeric; determined by author and by software (PISA)
Molecular Components in 8C2Z
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B
(Gene symbol: DYRK1B)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amineN-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
2
3
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303