8C1E: Aurora A kinase in complex with TPX2-inhibitor 9

PDB ID: 8C1EDownload
MMDB ID: 240931
PDB Deposition Date: 2022/12/20
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 2.798  Å
Source Organism:
Similar Structures:
Biological Unit for 8C1E: monomeric; determined by author and by software (PISA)
Molecular Components in 8C1E
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-(4-chloranyl-3-cyano-phenyl)-7-methyl-1~{H}-indole-6-carboxylic acid4-(4-chloranyl-3-cyano-phenyl)-7-methyl-1~{H}-indole-6-carboxylic acid
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303