8C08: Crystal structure of JAK2 JH2-K539L

PDB ID: 8C08Download
MMDB ID: 240480
PDB Deposition Date: 2022/12/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8C08: dimeric; determined by author and by software (PISA)
Molecular Components in 8C08
Label Count Molecule
Proteins (2 molecules)
2
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303