8BZB: co-soak stabilizers for ERa - 14-3-3 interaction (884_AZ275)

PDB ID: 8BZBDownload
MMDB ID: 233535
PDB Deposition Date: 2022/12/14
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8BZB: tetrameric; determined by author
Molecular Components in 8BZB
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
2
2
2-(4-chloranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide2-(4-chloranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide
3
2
4-ethoxy-1-benzothiophene-2-carboximidamide4-ethoxy-1-benzothiophene-2-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303