8BZA: single soak stabilizer for ERa - 14-3-3 interaction (AZ555)

PDB ID: 8BZADownload
MMDB ID: 233534
PDB Deposition Date: 2022/12/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.25  Å
Source Organism:
Similar Structures:
Biological Unit for 8BZA: tetrameric; determined by author
Molecular Components in 8BZA
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Eralpha Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
4-methyl-5-phenyl-thiophene-2-carboximidamide4-methyl-5-phenyl-thiophene-2-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303