8BX9: Crystal structure of JAK2 JH1 in complex with ilginatinib

PDB ID: 8BX9Download
MMDB ID: 240096
PDB Deposition Date: 2022/12/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8BX9: monomeric; determined by author
Molecular Components in 8BX9
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
IlginatinibIlginatinib
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303