8BX4: fragment-linked stabilizer for ERa - 14-3-3 interaction (1074392)

PDB ID: 8BX4Download
MMDB ID: 233517
PDB Deposition Date: 2022/12/7
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8BX4: tetrameric; determined by author and by software (PISA)
Molecular Components in 8BX4
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Eralpha Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-[3,4-bis(chloranyl)phenoxy]-~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]-2-methyl-propanamide2-[3,4-bis(chloranyl)phenoxy]-~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]-2-methyl-propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303