8BWH: Small molecule stabilizer for 14-3-3/ChREBP (Cmd 42)

PDB ID: 8BWHDownload
MMDB ID: 246013
PDB Deposition Date: 2022/12/6
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8BWH: tetrameric; determined by author
Molecular Components in 8BWH
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Carbohydrate-responsive Element-binding Protein
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
[2-[2-[[2,2-bis(fluoranyl)-2-(2-fluorophenyl)ethyl]amino]-2-oxidanylidene-ethoxy]phenyl]phosphonic acid[2-[2-[[2,2-bis(fluoranyl)-2-(2-fluorophenyl)ethyl]amino]-2-oxidanylidene-ethoxy]phenyl]phosphonic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303