8BU7: Structure of DDB1 bound to 21195-engaged CDK12-cyclin K

PDB ID: 8BU7Download
MMDB ID: 235381
PDB Deposition Date: 2022/11/30
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.245  Å
Source Organism:
Similar Structures:
Biological Unit for 8BU7: trimeric; determined by author
Molecular Components in 8BU7
Label Count Molecule
Proteins (3 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Cyclin-dependent Kinase 12
(Gene symbol: CDK12)
Molecule annotation
1
Cyclin-k
(Gene symbol: CCNK)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
1-[2,6-bis(chloranyl)phenyl]-6-[[4-(2-hydroxyethyloxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one1-[2,6-bis(chloranyl)phenyl]-6-[[4-(2-hydroxyethyloxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one
3
10
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303