8BSU: Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate and the positive allosteric modulator BPAM344 at 2.9A resolution

PDB ID: 8BSUDownload
MMDB ID: 239624
PDB Deposition Date: 2022/11/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8BSU: dimeric; determined by author
Molecular Components in 8BSU
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Receptor Ionotropic, Kainate 3
(Gene symbol: Grik3)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
2
4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
2
5
ZINC IONZINC ION
3
3
GLYCEROLGLYCEROL
4
3
CHLORIDE IONCHLORIDE ION
5
5
SULFATE IONSULFATE ION
6
2
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE
7
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303