8BPC: Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom

PDB ID: 8BPCDownload
MMDB ID: 229992
PDB Deposition Date: 2022/11/16
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8BPC: trimeric; determined by author
Molecular Components in 8BPC
Label Count Molecule
Proteins (3 molecules)
1
Isoform 2 of Paired Amphipathic Helix Protein Sin3b
(Gene symbol: SIN3B)
Molecule annotation
1
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
1
PHD Finger Protein 12
(Gene symbol: PHF12)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDEOCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE
2
3
ZINC IONZINC ION
3
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303