8BO6: COAGULATION FACTOR XI PROTEASE DOMAIN IN COMPLEX WITH ACTIVE SITE INHIBITOR 2

PDB ID: 8BO6Download
MMDB ID: 235373
PDB Deposition Date: 2022/11/14
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.25  Å
Source Organism:
Similar Structures:
Biological Unit for 8BO6: monomeric; determined by author and by software (PISA)
Molecular Components in 8BO6
Label Count Molecule
Protein (1 molecule)
1
Coagulation Factor XIA Light Chain
(Gene symbol: F11)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(~{E})-~{N}-[[5-(3-azanyl-1~{H}-indazol-6-yl)-4-chloranyl-1~{H}-imidazol-2-yl]methyl]-3-[5-chloranyl-2-(1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enamide (Link to PubChem not yet available)(~{E})-~{N}-[[5-(3-azanyl-1~{H}-indazol-6-yl)-4-chloranyl-1~{H}-imidazol-2-yl]methyl]-3-[5-chloranyl-2-(1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enamide
2
1
CITRIC ACID (Link to PubChem not yet available)CITRIC ACID
3
4
GLYCEROL (Link to PubChem not yet available)GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303