8BLA: Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation)

PDB ID: 8BLADownload
MMDB ID: 246874
PDB Deposition Date: 2022/11/9
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8BLA: pentameric; determined by author
Molecular Components in 8BLA
Label Count Molecule
Proteins (5 molecules)
5
5-hydroxytryptamine Receptor 3A
(Gene symbol: HTR3A)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
25
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
VortioxetineVortioxetine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303