8BJL: Human Aldose Reductase in Complex with a Ligand with a Fluoro-Indol-Acetic-Acid Structure (Schl44172)

PDB ID: 8BJLDownload
MMDB ID: 238419
PDB Deposition Date: 2022/11/4
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 0.97  Å
Source Organism:
Similar Structures:
Biological Unit for 8BJL: monomeric; determined by author
Molecular Components in 8BJL
Label Count Molecule
Protein (1 molecule)
1
Aldose Reductase
(Gene symbol: AKR1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (Link to PubChem not yet available)NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
2-(6-fluoranylindol-1-yl)ethanoic acid (Link to PubChem not yet available)2-(6-fluoranylindol-1-yl)ethanoic acid
3
1
DIMETHYL SULFOXIDE (Link to PubChem not yet available)DIMETHYL SULFOXIDE
4
1
CITRIC ACID (Link to PubChem not yet available)CITRIC ACID
5
1
DI(HYDROXYETHYL)ETHER (Link to PubChem not yet available)DI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303