8BI6: Crystal structure of human Choline Kinase A in complex with UNC0638

PDB ID: 8BI6Download
MMDB ID: 238412
PDB Deposition Date: 2022/11/1
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8BI6: dimeric; determined by software (PISA)
Molecular Components in 8BI6
Label Count Molecule
Proteins (2 molecules)
2
Choline Kinase Alpha
(Gene symbol: CHKA)
Molecule annotation
Chemicals and Non-standard biopolymers (27 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
3
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
6
4
PHOSPHATE IONPHOSPHATE ION
7
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303