8B8H: Structure of DCS-resistant variant D322N of alanine racemase from M. tuberculosis in complex with DCS

PDB ID: 8B8HDownload
MMDB ID: 228662
PDB Deposition Date: 2022/10/4
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 8B8H: dimeric; determined by author and by software (PISA)
Molecular Components in 8B8H
Label Count Molecule
Proteins (2 molecules)
2
Alanine Racemase
(Gene symbol: alr)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl-(3-oxidanyl-1,2-oxazol-4-yl)azanium[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl-(3-oxidanyl-1,2-oxazol-4-yl)azanium
2
2
(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium
3
1
CALCIUM IONCALCIUM ION
4
2
CHLORIDE IONCHLORIDE ION
5
1
GLYCEROLGLYCEROL
6
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303