8B6M: Tankyrase 2 in complex with an inhibitor

PDB ID: 8B6MDownload
MMDB ID: 236525
PDB Deposition Date: 2022/9/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8B6M: dimeric; determined by author
Molecular Components in 8B6M
Label Count Molecule
Proteins (2 molecules)
1
Poly [adp-ribose] Polymerase Tankyrase-2
(Gene symbol: TNKS2)
Molecule annotation
1
Poly [adp-ribose] Polymerase Tankyrase-2
(Gene symbol: TNKS2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
~{N}-(2-methoxyphenyl)-4-[[2-(4-oxidanylidene-3~{H}-quinazolin-2-yl)ethyl-(thiophen-2-ylmethyl)carbamoyl]amino]benzamide~{N}-(2-methoxyphenyl)-4-[[2-(4-oxidanylidene-3~{H}-quinazolin-2-yl)ethyl-(thiophen-2-ylmethyl)carbamoyl]amino]benzamide
2
2
SULFATE IONSULFATE ION
3
1
ZINC IONZINC ION
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303