8AYN: Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand LY3130481

PDB ID: 8AYNDownload
MMDB ID: 229204
PDB Deposition Date: 2022/9/2
Updated in MMDB: 2023/04
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8AYN: hexameric; determined by author
Molecular Components in 8AYN
Label Count Molecule
Proteins (6 molecules)
2
Isoform Flip of Glutamate Receptor 2
(Gene symbol: Gria2)
Molecule annotation
2
Voltage-dependent Calcium Channel Gamma-8 Subunit
(Gene symbol: Cacng8)
Molecule annotation
2
Isoform Flip of Glutamate Receptor 1
(Gene symbol: Gria1)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
4
{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
2
4
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
3
14
PALMITIC ACIDPALMITIC ACID
4
4
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
5
2
6-[(1~{S})-1-[1-[5-(2-hydroxyethyloxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3~{H}-1,3-benzothiazol-2-one6-[(1~{S})-1-[1-[5-(2-hydroxyethyloxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3~{H}-1,3-benzothiazol-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303