8AWR: Structure of recombinant human beta-glucocerebrosidase in complex with L-carbaxylosyl chloride

PDB ID: 8AWRDownload
MMDB ID: 243885
PDB Deposition Date: 2022/8/30
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.49  Å
Source Organism:
Similar Structures:
Biological Unit for 8AWR: monomeric; determined by author and by software (PISA)
Molecular Components in 8AWR
Label Count Molecule
Protein (1 molecule)
1
Lysosomal Acid Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
SULFATE IONSULFATE ION
5
23
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
(1~{S},2~{R},3~{S},6~{S})-6-chloranylcyclohex-4-ene-1,2,3-triol(1~{S},2~{R},3~{S},6~{S})-6-chloranylcyclohex-4-ene-1,2,3-triol
7
1
(1~{S},2~{S},3~{S},4~{R})-cyclohexane-1,2,3,4-tetrol(1~{S},2~{S},3~{S},4~{R})-cyclohexane-1,2,3,4-tetrol
8
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
9
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303