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8AVE:
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model)
PDB ID:
8AVE
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MMDB ID:
228651
PDB Deposition Date:
2022/8/26
Updated in MMDB:
2024/10
Experimental Method:
electron microscopy
Resolution:
5.62 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Molecular Components in 8AVE
Label
Count
Molecule
Proteins (4 molecules)
A
C
2
Leptin
(Gene symbol:
LEP
)
B
D
2
Leptin Receptor
(Gene symbol:
LEPR
)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303