8AQP: Structure of Human Aldose Reductase Mutant A299G/L300A with a Citrate Molecule Bound in the Anion Binding Pocket

PDB ID: 8AQPDownload
MMDB ID: 234444
PDB Deposition Date: 2022/8/13
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 0.96  Å
Source Organism:
Similar Structures:
Biological Unit for 8AQP: monomeric; determined by author and by software (PISA)
Molecular Components in 8AQP
Label Count Molecule
Protein (1 molecule)
1
Aldo-keto Reductase Family 1 Member B1
(Gene symbol: AKR1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
CITRIC ACIDCITRIC ACID
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303