8AKL: Acyl-enzyme complex of meropenem bound to deacylation mutant KPC-2 (E166Q)

PDB ID: 8AKLDownload
MMDB ID: 227528
PDB Deposition Date: 2022/7/29
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.35  Å
Source Organism:
Similar Structures:
Biological Unit for 8AKL: monomeric; determined by software (PISA)
Molecular Components in 8AKL
Label Count Molecule
Protein (1 molecule)
1
Carbapenem-hydrolyzing Beta-lactamase KPC
(Gene symbol: bla)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
GLYCEROLGLYCEROL
2
1
(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid
3
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303