8AKJ: Acyl-enzyme complex of cephalothin bound to deacylation mutant KPC-2 (E166Q)

PDB ID: 8AKJDownload
MMDB ID: 227526
PDB Deposition Date: 2022/7/29
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.35  Å
Source Organism:
Similar Structures:
Biological Unit for 8AKJ: dimeric; determined by software (PISA)
Molecular Components in 8AKJ
Label Count Molecule
Proteins (2 molecules)
2
Carbapenem-hydrolyzing Beta-lactamase KPC
(Gene symbol: bla)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
5
SULFATE IONSULFATE ION
2
6
GLYCEROLGLYCEROL
3
2
5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303